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Ativan

Generic Name: lorazepam (oral) (lor A ze pam)
Brand Names: Ativan

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Ativan is one of the most frequently prescribed psychotropic drugs. It is used to treat anxiety disorders and arrest epileptic status in adults and children. The efficacy of Ativan has been proven in two multi-center controlled trials, which included more than 170 patients.

 

Ativan belongs to the group of benzodiazepines with a short period of action. The active substance of the drug is the anxiolytic agent Lorazepam, which was developed by scientists at the end of the last century.

 

By suppressing the activity of the central nervous system, Ativan weakens the symptoms of anxiety and softens such manifestations, as:

 

  • cardiopalmus;
  • emotional stress;
  • nervousness and apathy;
  • sleep disturbances.

 

The use of Ativan helps suppress unnecessary excitation of the neurons in the cerebral cortex and weaken the polysynaptic spinal reflexes. The drug possesses the following effects:

 

  • soporific;
  • sedative;
  • anti-emetic;
  • anticonvulsant;
  • muscle relaxing.

 

Advantages of Ativan are low cumulative ability and short half-life. Unlike other benzodiazepines, Ativan is not metabolized in the liver, and is exposed to glucuronidation in the kidneys.

 

In this regard, Ativan is considered the safest among benzodiazepines. The drug is well tolerated by the elderly and patients with liver damage.

 

It has been established that the anxiolytic has a favorable profile of the effect over the patient’s cognitive functions. The therapeutic effect of Ativan is manifested even when applied in low doses.

 

Due to the action exerted, Ativan is prescribed for:

 

  • treatment of epileptic seizures;
  • premedication for the purpose of preparing the patient for surgical intervention, diagnostic procedures;
  • treatment of anxiety disorders and relief of acute attacks of anxiety, accompanied by sleep disturbances, emotional stress or depression.

 

In view of the fact that Ativan exerts a depressing effect over the central nervous system and has a high addictive potential, the drug is classified as a prescription drug.

 

To get a prescription and buy Ativan, you need to first consult with a specialist, who will assess the feasibility of the use of this psychoactive drug.

 

Depending on the specific situation, an experienced specialist will select the correct dosage, dosage regimen and dosage form of Ativan.

 

Patients with anxiety disorders can buy Ativan both in retail pharmacies and online. Online pharmacies provide an opportunity to buy anxiolytics from almost any country in the world.

 

Buying Ativan in an online pharmacy allows the patient to:

 

  • save time and money;
  • get a free consultation from a pharmacist;
  • order the anxiolytic at any time of the day;
  • get Ativan without leaving home.

 

If you were prescribed Ativan for the first time, check out the leaflet of this anxiolytic, find out its release forms and storage conditions before you place an order. Ativan can be sold in different dosage forms in different online pharmacies.

 

The following dosage forms are supplied to the world pharmaceutical market:

 

  • Oral Ativan tablets of 0.5 mg, 1 mg, and 2 mg;
  • Sublingual Ativan tablets of 0.5 mg, 1 mg, and 2 mg;
  • Ativan solution for injection of 2 mg/ml, and 4 mg/ml.

 

Tablets should be stored in a tightly closed container at room temperature. Solution for injection should be stored in the fridge and protected from direct sunlight.

 

Typically, Ativan injections are used for premedication. Injectable form of Ativan helps to quickly remove psychoemotional stress and feelings of fear and anxiety before a surgical intervention.

 

Ativan injections are also used as an emergency aid to relieve epileptic status in children and adults. Injections can be introduced both intravenously and intramuscularly.

 

The oral form of Ativan is approved for use in adults and adolescents over 12 years of age only for the treatment of anxiety disorders. The oral form of this anxiolytic can be used both in monotherapy and in combination with antidepressants.

 

Ativan dosage regimen for the treatment of anxiety disorders

 

Ativan dose for the treatment of anxiety is selected individually, depending on the patient’s clinical response to treatment. The recommended dose can vary in the range of 2-6 mg of Ativan per day.

 

The daily dose is divided into several intakes. It should be borne in mind that a large dose of Ativan should be taken immediately before bedtime. In an expressed state of anxiety and excitation, the daily dose can be increased to 10 mg of Ativan.

 

In the short-term treatment of insomnia, patients are prescribed 1 mg to 4 mg of Ativan before bedtime.

 

Ativan dosing regimen for arresting status epilepticus

 

Due to its short-term anticonvulsant action, Ativan is very effective for arresting epileptic status and helps to reduce the frequency of epileptic seizures.

 

Ativan is preferably introduced intravenously slowly, however, the anxiolytic can be administered intramuscularly when an intravenous catheter is inaccessible. The usual adult dose of Ativan is 4 mg, and the infant dose is 2 mg.

 

If epileptic seizures are not arrested, the patient is again injected with Ativan 10 minutes later. The effect of injections can last up to 8 hours.

 

When using Ativan, it is important to adhere to the recommended dosages and the duration of treatment. Despite the fact that Ativan has a short half-life, unreasonable use of the drug in high doses can cause serious side effects and drug dependence.

 

The development of side effects is most likely at the beginning of treatment. During this period, patients often experience increased fatigue, dizziness, tremor, cataplexy, and blood pressure lowering.

 

If you are prescribed Ativan, you should be aware of the fact that an abrupt cessation of the drug can lead to a return of the disease symptoms and cause withdrawal syndrome. Convulsions and impaired consciousness may develop in severe cases.

 

Therefore, Ativan should be discontinued gradually. Patients are also advised to refrain from driving motor vehicles within 3 days after the treatment cessation.

 

A timely start of Ativan therapy increases the chance for a successful treatment. To avoid wasting time searching for inexpensive Ativan in city pharmacies, order it online and reduce your expenses for anticonvulsant/anxiolytic therapy.

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